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学术讲座:Non-invasive brain stimulation in psychiatry
作者: 科研业务处 ║ 日期: 2016/08/30 

报告人:Prof. Andreas Jochen Fallgatter
    Director of the Dept. of Psychiatry, University of Tuebingen, Germany
时 间:2016年9月5日(周一),14:30
地 点:南楼6层会议室
报告摘要:
Objectives: Psychiatric disorders like depression, anxiety and schizophrenias are currently mainly treated with pharmacotherapeutic and psychotherapeutic methods. The success measured as improvement of symptoms under pharmacotherapeutic and psychotherapeutic treatment strategies is surprisingly good with high effect sizes (>0.8) in randomized controlled trials. However, there is still room and need for improvement.
Methods: Non-invasive brain stimulation methods like repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) are increasingly applied (1) in combination with neuroimaging methods like fMRI, NIRS or EEG in order to better understand the pathophysiological background of the above-mentioned psychiatric disorders or disorder-related symptoms and (2) as an alternative or add-on therapeutic approach.
Results: Evidence from multiple studies with rTMS and in the last years also with tDCS points to a major role of a dysfunction of the lateral prefrontal cortex in depression and anxiety and of the temporal cortex in auditory hallucinations in schizophrenic patients. Treatment protocols with rTMS and tDCS focussing on a functional improvement of these brain regions in the respective disorders provide first evidence for a therapeutic application.
Conclusion: Both rTMS and tDCS are of increasing importance as methods for an improved understanding of the brain pathophysiology underlying depression, anxiety and schizophrenias as well as methods suitable for a direct therapeutic application in these disorders.

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