主要研究方向为生物信息学、统计遗传学、中西医结合。在国际上首次鉴别出干燥综合征（Sj？gren's syndrome）的易感基因区域7q11.23。已发表学术论文40余篇，其中第一/并列第一作者、通讯/并列通讯作者的文章发表在《自然-遗传学》（Nature Genetics）、《科学通报》（Chinese Science Bulletin）、《核酸研究》（Nucleic Acids Research）、心理神经内分泌学（Psychoneuroendocrinology）、药理学研究（Pharmacological Research）、《天津中医药》等学术刊物。
2. 获青年学者奖金参加第14届逆转录病毒及机会型感染学术会议(CROI 2007, 洛杉矶)。
（# 并列第一作者，* 通讯作者）：
1. Gao J#, Zhang K#, Wang Y#, Guo R, Liu H, Jia C, Sun X, Wu C, Wang W, Du J, Chen J*. (2020). A Machine Learning-driven Study Indicates Emodin Improves Cardiac Hypertrophy by Modulation of Mitochondrial SIRT3 Signaling. Pharmacological Research 155:104739. doi: 10.1016/j.phrs.2020.104739
2. 张昆林，孙鹏程，陈雪梅，陈建新，张妍，王一，王济*，王琦*。（2021）。基于生物信息学方法的祛风解表中药干预过敏体质机制研究。天津中医药 38(3):273-279。DOI: 10.11656/j.issn.1672-1519.2021.03.01
3. Zhang K#, Qu S#, Chang S#, Li G, Cao C, Fang K, Olff M, Wang L*, Wang J*. (2017). An overview of posttraumatic stress disorder genetic studies by analyzing and integrating genetic data into genetic database PTSDgene. Neuroscience and Biobehavioral Reviews 83:647-656. doi: 10.1016/j.neubiorev.2017.08.021
4. Zhang K#, Chang S#, Guo L, Wang J*. (2015). I-GSEA4GWAS v2: a web server for functional analysis of SNPs in trait-associated pathways identified from genome-wide association study. Protein & Cell 6(3):221-224. doi: 10.1007/s13238-014-0114-4
5. Li Y#, Zhang K#, Chen H#, Sun F, Xu J, Wu Z, Li P, Zhang L, Du Y, Luan H, Li X, Wu L, Li H, Wu H, Li X, Li X, Zhang X, Gong L, Dai L, Sun L, Zuo X, Xu J, Gong H, Li Z, Tong S, Wu M, Li X, Xiao W, Wang G, Zhu P, Shen M, Liu S, Zhao D, Liu W, Wang Y, Huang C, Jiang Q, Liu G, Liu B, Hu S, Zhang W, Zhang Z, You X, Li M, Hao W, Zhao C, Leng X, Bi L, Wang Y, Zhang F, Shi Q, Qi W, Zhang X, Jia Y, Su J, Li Q, Hou Y, Wu Q, Xu D, Zheng W, Zhang M, Wang Q, Fei Y, Zhang X, Li J, Jiang Y, Tian X, Zhao L, Wang L, Zhou B, Li Y, Zhao Y, Zeng X, Ott J, Wang J*, Zhang F*. (2013). A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sj？gren's syndrome at 7q11.23. Nature Genetics 45(11):1361-1365. doi: 10.1038/ng.2779