研究队伍
简历
胡理，中国科学院心理研究所研究员，中国科学院大学岗位教师，博士生导师，国家自然科学基金委优秀青年科学基金获得者，获中科院朱李月华优秀教师奖，中国科学院教育教学成果奖二等奖，中国科学院大学领雁银奖，首届“瀚翔”青年科学家奖等。主要关注疼痛和情绪信息编码与调节的认知神经机制，通过跨物种的研究手段，结合多模态脑影像和认知神经调控技术，研究疼痛和情绪信息处理的脑神经机制，搭建疼痛大数据信息化平台，并基于此开发人体疼痛评测系统和基于多模态生理信号的负性情绪自动识别与调控系统。此外，重点探索缓解疼痛、改善情绪的认知神经调控技术，为减轻痛苦和舒缓情绪提供了有效的策略。近年来，先后主持了国家自然科学基金、国家重点研发计划、世界疼痛研究学会国际合作基金等多个研究项目/课题；在Molecular Psychiatry、Trends in Neurosciences、PNAS、Nature Communications和Journal of Neuroscience等权威期刊发表了100多篇学术论文；申请发明专利5项，获批计算机软件著作权登记2项；出版中英文专著3部（《EEG Signal Processing and Feature Extraction》、《脑电信号处理与特征提取》、《疼痛认知神经科学》）。
教育及工作经历：
2001-2005 天津大学 自动化 学士
2005-2007 天津大学 检测技术及自动化装置 硕士
2007-2010 香港大学 生物医学工程 博士
2009-2010 University of Oxford 访问学者
2010-2011 University College London 访问学者
2011-2016 西南大学 研究员
2016-今 中国科学院心理研究所 研究员
研究领域
疼痛与共情、疼痛和情绪调节、认知调控、神经调控、脑神经信号分析与特征提取
社会任职
获奖及荣誉
代表论著
1. Wang, H.L., Guo, Y.F., Tu, Y.H., Peng, W.W., Lu, X.J., Bi, Y.Z., Iannetti, G.D., Hu, L.#, 2022. Neural processes responsible for the translation of sustained nociceptive inputs into subjective pain experience. Cerebral Cortex, doi.org/10.1093/cercor/bhac090.
2. Ren, Q.Y., Yang, Y., Wo, Y., Lu, X.J., Hu, L., 2021. Different priming effects of empathy on neural processing associated with first-hand pain and nonpain perception. Annals of the New York Academy of Sciences, doi.org/10.1111/nyas.14723.
3. Zhang, H.J., Bi, Y.Z., Hou, X., Lu, X.J., Tu, Y.H., Hu, L.#, 2021. The role of negative emotions in sex differences in pain sensitivity. NeuroImage, 245, 118685.
4. Fu, Z.N., Tu, Y.H., Calhoun, V.D., Zhang, Y.Q., Zhao, Q., Chen, J., Meng, Q.T., Lu, Z.J., Hu, L.#, 2021. Dynamic functional connectivity associated with post-traumatic stress symptoms in COVID-19 survivors. Neurobiology of Stress, 15, 100377.
5. Tu, Y.H., Zhang, Y.Q., Li, Y., Zhao, Q., Bi, Y.Z., Lu, X.J., Kong, Y.Z., Wang, L., Lu, Z.J., Hu, L.#, 2021. Post-traumatic stress symptoms in COVID-19 survivors: a self-report and brain imaging follow-up study. Molecular Psychiatry, 1-6.
6. Wang, F.X., Zhang, L.B., Yue, L.P., Zeng, Y.X., Zhao, Q., Gong, Q.J., Zhang, J.B., Liu, D.Y., Lin, C.Y., Luo, X.Y., Xia, X.L., Wan, L., Hu, L.#, 2021. A Novel Method to Simultaneously Record Spinal Cord Electrophysiology and Electroencephalography Signals. NeuroImage, 232, 117892.
7. Lu, X.J., Yao, X.R., Thompson, W.F., Hu, L.#, 2021. Movement-induced analgesia: Behavioral characteristics and neural mechanisms. Annals of the New York Academy of Sciences, 1497 (1), 39-56.
8. Tu, Y.H., Gao, J., Bi, Y.Z., Hu, L.#, 2020. Magnetic resonance imaging for chronic pain: diagnosis, manipulation, and biomarkers. SCIENCE CHINA Life Sciences, 64 (6), 879-896.
9. Li, H., Li, X.Y., Gao, F., Kong, Y.Z., Hu, L., 2020. Deficits in ascending and descending pain modulation pathways in patients with postherpetic neuralgia. NeuroImage, 221, 117186.
10. Yue, L.P., Iannetti, G.D., Hu, L.#, 2020. The neural origin of nociceptive-induced gamma band oscillations. Journal of Neuroscience, 40 (17), 3478-3490.
11. Zhou, L.L., Bi, Y.Z., Liang, M., Kong, Y.Z., Tu, Y.H., Zhang, X.Y., Song, Y.Y., Du, X., Tan, S.P., Hu, L.#, 2020. A modality-specific dysfunction of pain processing in schizophrenia. Human Brain Mapping, 41 (7), 1738-1753.
12. Tu, Y.H., Bi, Y.Z., Zhang, L.B., Wei, H., Hu, L.#, 2020. Mesocorticolimbic pathways encode cue-based expectancy effects on pain. Journal of Neuroscience, 40(2):382-394.
13. Hu, L.#, Iannetti, G.D., 2019. Neural indicators of perceptual variability of pain across species. PNAS, 116(5): 1782-1791.
14. Peng, W.W., Tang, Z.Y., Zhang, F.R., Li, H., Kong, Y.Z., Iannetti, G.D., Hu, L.#, 2019. Neurobiological mechanisms of TENS-induced analgesia. NeuroImage, 195:396-408.
15. Jin, Q.Q., Wu, G.Q., Peng, W.W., Xia, X.L., Hu, L.#, Iannetti, G.D., 2018. Somatotopic representation of second pain in the primary somatosensory cortex of humans and rodents. The Journal of Neuroscience, 38(24): 5538-5550.
16. Peng, W.W., Xia, X.L., Yi, M., Zhang, Z.G., Huang, G., Iannetti, G.D., Hu, L.#, 2018. Brain oscillations reflecting pain-related behavior in freely-moving rats. Pain, 159(1): 106-118.
17. Liu, J.X., Liu, H.J., Mu, J.Y., Xu, Q., Chen, T., Dun, W.H., Yang, J., Tian, J., Hu, L.#, Zhang, M., 2016. Altered white matter microarchitecture in the cingulum bundle in women with primary dysmenorrhea: a tract-based analysis study. Human Brain Mapping, 38(9):4430-4443.
18. Hu, L.#, Iannetti, G.D., 2016. Painful issues in pain prediction. Trends in Neurosciences, 39(4): 212-220.
19. Hu, L.#, Iannetti, G.D., 2016. Issues in pain prediction – beyond pain and gain. Trends in Neurosciences, 39(10): 640-642.
20. Xia, X.L., Peng, W.W., Iannetti, G.D., Hu, L.#, 2016. Laser-evoked cortical responses in freely-moving rodents reflect the activation of C-fibre afferent pathways. NeuroImage, 128: 209-217.
21. Tu, Y.H., Zhang, Z.G., Tan, A., Peng, W.W., Hung, Y.S., Moayedi, M., Iannetti, G.D., Hu, L.#, 2016. Alpha and Gamma Oscillation Amplitudes Synergistically Predict the Perception of Forthcoming Nociceptive Stimuli. Human Brain Mapping, 37 (2), 501-514.
22. Hu, L.#, Xia, X.L., Peng, W.W., Su, W.X., Luo, F., Yuan, H., Chen, A.T., Liang, M., Iannetti, G.D., 2015. Was It a Pain or a Sound? Across-species Variability in Sensory Sensitivity. Pain, 156 (12), 2449-2457.
23. Hu, L.#, Zhang, L., Chen, R., Yu, H.B., Li, H., Mouraux, A., 2015. The primary somatosensory cortex and the insula contribute differently to the processing of transient and sustained nociceptive and non-nociceptive somatosensory inputs. Human Brain Mapping, 36 (11), 4346-4360.
24. Hu, L.#, Zhang, Z.G., Mouraux, A., Iannetti, G.D., 2015. Multiple linear regression to estimate time-frequency electrophysiological responses in single trials. NeuroImage, 111: 442-453.
25. Hu, L.#, Cai, M.M., Xiao, P., Luo, F., Iannetti, G.D., 2014. Human Brain Responses to Concomitant Stimulation of Aδ and C Nociceptors. The Journal of Neuroscience, 34 (34): 11439-11451.
26. Hu, L.#, Xiao, P., Zhang, Z.G., Mouraux, A., Iannetti, G.D., 2014. Single-trial time-frequency analysis of electrocortical signals: baseline correction and beyond. NeuroImage, 84: 876–887.
27. Hu, L.#, Valentini, E., Zhang, Z.G., Liang, M., Iannetti, G.D., 2014. The primary somatosensory cortex contributes to the latest part of the cortical response elicited by nociceptive somatosensory stimuli in humans. NeuroImage, 84: 383–393.
28. Huang, G., Xiao, P., Iannetti, G.D., Zhang, Z.G., Hu, L.#, 2013. A novel approach to predict subjective pain perception from single-trial laser-evoked potentials. NeuroImage, 81:283-293.
29. Liang, M., Mouraux, A., Hu, L., Iannetti, G.D., 2013. Primary Sensory Cortices Contain Distinguishable Spatial Patterns of Activity for Each Sense. Nature Communications, 4:1979.
30. Zhang, Z.G.*, Hu, L.*, Hung, Y.S., Mouraux, A., Iannetti, G.D., 2012. Gamma-band oscillations in the primary somatosensory cortex – a direct and obligatory correlate of subjective pain intensity. The Journal of Neuroscience, 32(22):7429-7438.
31. Hu, L., Zhang, Z.G., Hu, Y., 2012. A Time-Varying Source Connectivity Approach to Reveal Human Somatosensory Information Processing. NeuroImage, 62:217-228.
32. Valentini, E.*, Hu, L.*, Chakrabarti, B., Aglioti, S.M., Hu, Y., Iannetti, G.D., 2012. The primary somatosensory cortex largely contributes to the early part of the cortical response elicited by nociceptive stimuli. NeuroImage, 59(2):1571-81.
33. Hu, L., Mouraux, A., Hu, Y., Iannetti, G.D., 2010. A novel approach for enhancing the signal-to-noise ratio and detecting automatically event-related potentials (ERPs) in single trials. NeuroImage 50, 99-111.
2. Ren, Q.Y., Yang, Y., Wo, Y., Lu, X.J., Hu, L., 2021. Different priming effects of empathy on neural processing associated with first-hand pain and nonpain perception. Annals of the New York Academy of Sciences, doi.org/10.1111/nyas.14723.
3. Zhang, H.J., Bi, Y.Z., Hou, X., Lu, X.J., Tu, Y.H., Hu, L.#, 2021. The role of negative emotions in sex differences in pain sensitivity. NeuroImage, 245, 118685.
4. Fu, Z.N., Tu, Y.H., Calhoun, V.D., Zhang, Y.Q., Zhao, Q., Chen, J., Meng, Q.T., Lu, Z.J., Hu, L.#, 2021. Dynamic functional connectivity associated with post-traumatic stress symptoms in COVID-19 survivors. Neurobiology of Stress, 15, 100377.
5. Tu, Y.H., Zhang, Y.Q., Li, Y., Zhao, Q., Bi, Y.Z., Lu, X.J., Kong, Y.Z., Wang, L., Lu, Z.J., Hu, L.#, 2021. Post-traumatic stress symptoms in COVID-19 survivors: a self-report and brain imaging follow-up study. Molecular Psychiatry, 1-6.
6. Wang, F.X., Zhang, L.B., Yue, L.P., Zeng, Y.X., Zhao, Q., Gong, Q.J., Zhang, J.B., Liu, D.Y., Lin, C.Y., Luo, X.Y., Xia, X.L., Wan, L., Hu, L.#, 2021. A Novel Method to Simultaneously Record Spinal Cord Electrophysiology and Electroencephalography Signals. NeuroImage, 232, 117892.
7. Lu, X.J., Yao, X.R., Thompson, W.F., Hu, L.#, 2021. Movement-induced analgesia: Behavioral characteristics and neural mechanisms. Annals of the New York Academy of Sciences, 1497 (1), 39-56.
8. Tu, Y.H., Gao, J., Bi, Y.Z., Hu, L.#, 2020. Magnetic resonance imaging for chronic pain: diagnosis, manipulation, and biomarkers. SCIENCE CHINA Life Sciences, 64 (6), 879-896.
9. Li, H., Li, X.Y., Gao, F., Kong, Y.Z., Hu, L., 2020. Deficits in ascending and descending pain modulation pathways in patients with postherpetic neuralgia. NeuroImage, 221, 117186.
10. Yue, L.P., Iannetti, G.D., Hu, L.#, 2020. The neural origin of nociceptive-induced gamma band oscillations. Journal of Neuroscience, 40 (17), 3478-3490.
11. Zhou, L.L., Bi, Y.Z., Liang, M., Kong, Y.Z., Tu, Y.H., Zhang, X.Y., Song, Y.Y., Du, X., Tan, S.P., Hu, L.#, 2020. A modality-specific dysfunction of pain processing in schizophrenia. Human Brain Mapping, 41 (7), 1738-1753.
12. Tu, Y.H., Bi, Y.Z., Zhang, L.B., Wei, H., Hu, L.#, 2020. Mesocorticolimbic pathways encode cue-based expectancy effects on pain. Journal of Neuroscience, 40(2):382-394.
13. Hu, L.#, Iannetti, G.D., 2019. Neural indicators of perceptual variability of pain across species. PNAS, 116(5): 1782-1791.
14. Peng, W.W., Tang, Z.Y., Zhang, F.R., Li, H., Kong, Y.Z., Iannetti, G.D., Hu, L.#, 2019. Neurobiological mechanisms of TENS-induced analgesia. NeuroImage, 195:396-408.
15. Jin, Q.Q., Wu, G.Q., Peng, W.W., Xia, X.L., Hu, L.#, Iannetti, G.D., 2018. Somatotopic representation of second pain in the primary somatosensory cortex of humans and rodents. The Journal of Neuroscience, 38(24): 5538-5550.
16. Peng, W.W., Xia, X.L., Yi, M., Zhang, Z.G., Huang, G., Iannetti, G.D., Hu, L.#, 2018. Brain oscillations reflecting pain-related behavior in freely-moving rats. Pain, 159(1): 106-118.
17. Liu, J.X., Liu, H.J., Mu, J.Y., Xu, Q., Chen, T., Dun, W.H., Yang, J., Tian, J., Hu, L.#, Zhang, M., 2016. Altered white matter microarchitecture in the cingulum bundle in women with primary dysmenorrhea: a tract-based analysis study. Human Brain Mapping, 38(9):4430-4443.
18. Hu, L.#, Iannetti, G.D., 2016. Painful issues in pain prediction. Trends in Neurosciences, 39(4): 212-220.
19. Hu, L.#, Iannetti, G.D., 2016. Issues in pain prediction – beyond pain and gain. Trends in Neurosciences, 39(10): 640-642.
20. Xia, X.L., Peng, W.W., Iannetti, G.D., Hu, L.#, 2016. Laser-evoked cortical responses in freely-moving rodents reflect the activation of C-fibre afferent pathways. NeuroImage, 128: 209-217.
21. Tu, Y.H., Zhang, Z.G., Tan, A., Peng, W.W., Hung, Y.S., Moayedi, M., Iannetti, G.D., Hu, L.#, 2016. Alpha and Gamma Oscillation Amplitudes Synergistically Predict the Perception of Forthcoming Nociceptive Stimuli. Human Brain Mapping, 37 (2), 501-514.
22. Hu, L.#, Xia, X.L., Peng, W.W., Su, W.X., Luo, F., Yuan, H., Chen, A.T., Liang, M., Iannetti, G.D., 2015. Was It a Pain or a Sound? Across-species Variability in Sensory Sensitivity. Pain, 156 (12), 2449-2457.
23. Hu, L.#, Zhang, L., Chen, R., Yu, H.B., Li, H., Mouraux, A., 2015. The primary somatosensory cortex and the insula contribute differently to the processing of transient and sustained nociceptive and non-nociceptive somatosensory inputs. Human Brain Mapping, 36 (11), 4346-4360.
24. Hu, L.#, Zhang, Z.G., Mouraux, A., Iannetti, G.D., 2015. Multiple linear regression to estimate time-frequency electrophysiological responses in single trials. NeuroImage, 111: 442-453.
25. Hu, L.#, Cai, M.M., Xiao, P., Luo, F., Iannetti, G.D., 2014. Human Brain Responses to Concomitant Stimulation of Aδ and C Nociceptors. The Journal of Neuroscience, 34 (34): 11439-11451.
26. Hu, L.#, Xiao, P., Zhang, Z.G., Mouraux, A., Iannetti, G.D., 2014. Single-trial time-frequency analysis of electrocortical signals: baseline correction and beyond. NeuroImage, 84: 876–887.
27. Hu, L.#, Valentini, E., Zhang, Z.G., Liang, M., Iannetti, G.D., 2014. The primary somatosensory cortex contributes to the latest part of the cortical response elicited by nociceptive somatosensory stimuli in humans. NeuroImage, 84: 383–393.
28. Huang, G., Xiao, P., Iannetti, G.D., Zhang, Z.G., Hu, L.#, 2013. A novel approach to predict subjective pain perception from single-trial laser-evoked potentials. NeuroImage, 81:283-293.
29. Liang, M., Mouraux, A., Hu, L., Iannetti, G.D., 2013. Primary Sensory Cortices Contain Distinguishable Spatial Patterns of Activity for Each Sense. Nature Communications, 4:1979.
30. Zhang, Z.G.*, Hu, L.*, Hung, Y.S., Mouraux, A., Iannetti, G.D., 2012. Gamma-band oscillations in the primary somatosensory cortex – a direct and obligatory correlate of subjective pain intensity. The Journal of Neuroscience, 32(22):7429-7438.
31. Hu, L., Zhang, Z.G., Hu, Y., 2012. A Time-Varying Source Connectivity Approach to Reveal Human Somatosensory Information Processing. NeuroImage, 62:217-228.
32. Valentini, E.*, Hu, L.*, Chakrabarti, B., Aglioti, S.M., Hu, Y., Iannetti, G.D., 2012. The primary somatosensory cortex largely contributes to the early part of the cortical response elicited by nociceptive stimuli. NeuroImage, 59(2):1571-81.
33. Hu, L., Mouraux, A., Hu, Y., Iannetti, G.D., 2010. A novel approach for enhancing the signal-to-noise ratio and detecting automatically event-related potentials (ERPs) in single trials. NeuroImage 50, 99-111.
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