中国科学院心理研究所二级研究员，博士研究生导师。2000年于中国科学院心理研究所获理学博士学位。2001-2007先后在瑞典斯德哥尔摩大学心理系、英国伦敦学院大学认知神经科学研究所、美国阿肯色医科大学老化研究所从事博士后研究工作。2007年2月入选中国科学院心理研究所特聘研究员，负责组建老年心理研究中心，现任中心主任。
1．认知年老化及其脑神经机制研究；
2．老年期痴呆和抑郁的早期识别与干预；
3．认知年老化的跨文化研究；
4. 我国老年心理健康模型及其相关因素研究。
作为负责人，完成科技部重点研发计划课题1项，北京市重点科技计划2项，以及国家自然科学基金委项目11项。发表学术论文180余篇、团体标准4项、专家共识1项，获专利授权4项、著作登记21项。
主要研究成果：（1）基于对认知年老化脑神经机制及其可塑性研究发表数十篇高影响力SCI/SSCI论文，原创性发现被写入国际脑科学专著；（2）构建“多维分层老年认知障碍筛查模型”、完成“中国老年认知障碍风险评估技术规范”；（3）开展从认知训练、有氧运动，到认知+运动联合训练、多感官认知刺激疗法、经颅磁/电刺激以及综合干预研究共计十余项，深入揭示了各种干预方式的效果量和作用机制。完成“预防老年痴呆的社区综合干预实施指南”、“老年心理健康评估与促进平台”。为促进我国老年脑认知健康和认知障碍康复提供了技术。
代表论著
1. Liu, X., Ma, Z., Zhu, X., Zheng, Z., Li, J., Fu, J., ... & Li, J. (2023). Cognitive Benefit of a Multidomain Intervention for Older Adults at Risk of Cognitive Decline: A Cluster-Randomized Controlled Trial. The American Journal of Geriatric Psychiatry, 31(3), 197-209.？
2. Yin, S., Xiao, J., Zhu, X., Li, R., & Li, J. (2023). Improved Mood Boosts Memory Training Gains in Older Adults with Subjective Memory Complaints via Enhanced Amygdala-hippocampal Connectivity. The American Journal of Geriatric Psychiatry.
3. Zheng, Z., Zhao, X., Cui, X., Liu, X., Zhu, X., Jiang, Y., & Li, J. (2023). Subtle Pathophysiological Changes in Working Memory–Related Potentials and Intrinsic Theta Power in Community-Dwelling Older Adults with Subjective Cognitive Decline. Innovation in Aging, 7(2), igad004.
4. Huang, Y., Zhu, X., Liu, X., & Li, J. (2023). The effects of loneliness, social isolation, and associated gender differences on the risk of developing cognitive impairment for Chinese oldest old. Aging & Mental Health, 27(7), 1360-1367.？
5. Cui, X., Gui, W., Miao, J., Liu, X., Zhu, X., Zheng, Z., ... & Li, J. (2023). A combined intervention of aerobic exercise and video game in older adults: the efficacy and neural basis on improving mnemonic discrimination. The Journals of Gerontology: Series A, 78(8), 1436-1444.
6. Chen, S., Cai, Z., Hou, J., Lang, M., Zheng, Z., Zhu, X., & Li, J. (2022). Long-term effects of mnemonic training in healthy older adults: A meta-analysis. Psychology and Aging.
7. Yin, S., Zhu, X., Li, R., Huo, L., Ren, W., Niu, Y., & Li, J. (2022). Alleviated anxiety boosts memory training gain in older adults with subjective memory complaints: a randomized controlled trial. The American Journal of Geriatric Psychiatry, 30(2), 184-194.
8. Zhu, X., Yin, S., Huo, L., Zheng, Z., & Li, J. (2022). A multimodal intervention to improve cognition in community-dwelling older adults. The American Journal of Geriatric Psychiatry, 30(9), 1003-1014.
9. Huo, L., Zhu, X., Zheng, Z., Ma, J., Ma, Z., Gui, W., & Li, J. (2021). Effects of transcranial direct current stimulation on episodic memory in older adults: a meta-analysis. The Journals of Gerontology: Series B, 76(4), 692-702.
10. . Huo, L., Zheng, Z., Huang, J., Li, R., Li, J., & Li, J. (2020). Transcranial direct current stimulation enhances episodic memory in healthy older adults by modulating retrieval-specific activation. Neural Plasticity, 2020.
11. Li, R., Zhang, S., Yin, S., Ren, W., He, R., & Li, J. (2018). The fronto‐insular cortex causally mediates the default‐mode and central‐executive networks to contribute to individual cognitive performance in healthy elderly. Human brain mapping, 39(11), 4302-4311.
12. Li, J., Broster, L. S., Jicha, G. A., Munro, N. B., Schmitt, F. A., Abner, E., ... & Jiang, Y. (2017). A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging. Alzheimer's research & therapy, 9, 1-10.
13. Zhu, X., Yin, S., Lang, M., He, R., & Li, J. (2016). The more the better? A meta-analysis on effects of combined cognitive and physical intervention on cognition in healthy older adults. Ageing Research Reviews, 31, 67-79.
14. Zheng, Z., Li, J., Xiao, F., Ren, W., & He, R. (2016). Unitization improves source memory in older adults: An event-related potential study. Neuropsychologia, 89, 232-244.
15. Zheng, Z., Li, J., Xiao, F., Broster, L. S., & Jiang, Y. (2015). Electrophysiological evidence for the effects of unitization on associative recognition memory in older adults. Neurobiology of Learning and Memory, 121, 59-71.
16. Zheng, Z., Zhu, X., Yin, S., Wang, B., Niu, Y., Huang, X., ... & Li, J. (2015). Combined cognitive-psychological-physical intervention induces reorganization of intrinsic functional brain architecture in older adults. Neural plasticity, 2015.
17. Dai, B., Li, J., Chen, T., & Li, Q. (2015). Interpretive bias of ambiguous facial expressions in older adults with depressive symptoms. PsyCh journal, 4(1), 28-37.
18. Yin, S., Zhu, X., Li, R., Niu, Y., Wang, B., Zheng, Z., ... & Li, J. (2014). Intervention-induced enhancement in intrinsic brain activity in healthy older adults. Scientific reports, 4(1), 7309.
19. Li, R., Zhu, X., Yin, S., Niu, Y., Zheng, Z., Huang, X., ... & Li, J. (2014). Multimodal intervention in older adults improves resting-state functional connectivity between the medial prefrontal cortex and medial temporal lobe. Frontiers in aging neuroscience, 6, 39.
20. Yu, J., Su, T., Zhou, T., He, Y., Lu, J., Li, J., & He, R. (2014). Uric formaldehyde levels are negatively correlated with cognitive abilities in healthy older adults. Neuroscience Bulletin, 30, 172-184.
21. Cuijpers, P., Vogelzangs, N., Twisk, J., Kleiboer, A., Li, J., & Penninx, B. W. (2014). Comprehensive meta-analysis of excess mortality in depression in the general community versus patients with specific illnesses. American journal of psychiatry, 171(4), 453-462.
22. Wang, P., Li, J., Li, H., Li, B., Jiang, Y., Bao, F., & Zhang, S. (2013). Is emotional memory enhancement preserved in amnestic mild cognitive impairment? Evidence from separating recollection and familiarity. Neuropsychology, 27(6), 691.
23. Yang, L., Li, J., Spaniol, J., Hasher, L., Wilkinson, A. J., Yu, J., & Niu, Y. (2013). Aging, culture, and memory for socially meaningful item-context associations: an east-west cross-cultural comparison study. PloS one, 8(4), e60703.
24. Xiao, S., Li, J., Tang, M., Chen, W., Bao, F., Wang, H., ... & Zhang, M. (2013). Methodology of China's national study on the evaluation, early recognition, and treatment of psychological problems in the elderly: the China Longitudinal Aging Study (CLAS). Shanghai Archives of Psychiatry, 25(2), 91.
25. Yu, J., Li, J., & Huang, X. (2012). The Beijing version of the Montreal Cognitive Assessment as a brief screening tool for mild cognitive impairment: a community-based study. BMC psychiatry, 12, 1-8.
26. Chen, T. J., Li, H. J., & Li, J. (2012). The effects of reminiscence therapy on depressive symptoms of Chinese elderly: study protocol of a randomized controlled trial. BMC psychiatry, 12(1), 1-6.
27. Yu, J., Li, J., Cuijpers, P., Wu, S., & Wu, Z. (2012). Prevalence and correlates of depressive symptoms in Chinese older adults: A population‐based study. International journal of geriatric psychiatry, 27(3), 305-312.
28. Li, H., Li, J., Li, N., Li, B., Wang, P., & Zhou, T. (2011). Cognitive intervention for persons with mild cognitive impairment: A meta-analysis. Ageing research reviews, 10(2), 285-296.
29. Cuijpers, P., Li, J., Hofmann, S. G., & Andersson, G. (2010). Self-reported versus clinician-rated symptoms of depression as outcome measures in psychotherapy research on depression: a meta-analysis. Clinical psychology review, 30(6), 768-778.
30. Cuijpers, P., Donker, T., van Straten, A., Li, J., & Andersson, G. (2010). Is guided self-help as effective as face-to-face psychotherapy for depression and anxiety disorders? A systematic review and meta-analysis of comparative outcome studies. Psychological medicine, 40(12), 1943-1957.
31. Morcom, A. M., Li, J., & Rugg, M. D. (2007). Age effects on the neural correlates of episodic retrieval: increased cortical recruitment with matched performance. Cerebral cortex, 17(11), 2491-2506.
32. Li, J., Morcom, A. M., & Rugg, M. D. (2004). The effects of age on the neural correlates of successful episodic retrieval: an ERP study. Cognitive, Affective, & Behavioral Neuroscience, 4(3), 279-293.
33. Li, J., Nilsson, L. G., & Wu, Z. (2004). Effects of age and anxiety on episodic memory: Selectivity and variability. Scandinavian journal of psychology, 45(2), 123-129.